International Journal of Infertility & Fetal Medicine

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VOLUME 15 , ISSUE 2 ( May-August, 2024 ) > List of Articles

RESEARCH ARTICLE

Genital Tract Infections and Their Correlation with Sociodemographic Features among Infertile Women at a Tertiary Care Center

Diksha Shukla, Raj Kumar Kalyan, Prashant Gupta, Vimala Venkatesh, Renu Kumari, Sujata Deo, Anjoo Agarwal, Swastika Survirya

Keywords : Assisted reproductive technology, Chlamydia trachomatis, Ectopic pregnancy, Genital tract infections, Infertility, In vitro fertilization

Citation Information : Shukla D, Kalyan RK, Gupta P, Venkatesh V, Kumari R, Deo S, Agarwal A, Survirya S. Genital Tract Infections and Their Correlation with Sociodemographic Features among Infertile Women at a Tertiary Care Center. Int J Infertil Fetal Med 2024; 15 (2):65-70.

DOI: 10.5005/jp-journals-10016-1336

License: CC BY-NC 4.0

Published Online: 28-10-2024

Copyright Statement:  Copyright © 2024; The Author(s).


Abstract

In developing nations like India, genital tract infections (GTI) among women remain an underdiagnosed condition until they progress into complications. This study was planned to study GTI among infertile women attending infertility clinics. Samples from 105 married women for diagnosis of gonorrhea, Chlamydia trachomatis, candidiasis, trichomoniasis, bacterial vaginosis, syphilis, human immunodeficiency viruses (HIV), and hepatitis B were processed. The overall prevalence of reproductive tract infection (RTI) in the study population was 17.1% and the prevalence of chlamydial infection was 8.6%. Rural locality and illiteracy were found to be significantly correlated with infertility. The prevalence of different RTIs was candidiasis (10.5%), genital chlamydiosis (8.6%), bacterial vaginosis (5.7%), syphilis (2.9%), and gonorrhea (1%). Sociodemographic factors significantly correlated with Chlamydia trachomatis were positive history of RTI/sexually transmitted infection (STI) in the husband (72.2%), lower age-group, (44.4%), rural locality (100%), illiteracy (77.8%), and duration of marriage <5 years (44.4%). The genital discharge was the most common presentation.


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  1. Patel DA, Burnett NM, Curtis KM, et al. Reproductive tract infections. 2003.
  2. Rowley J, Vander Hoorn S, Korenromp E, et al. Chlamydia, gonorrhoea, trichomoniasis and syphilis: global prevalence and incidence estimates, 2016. Bull World Health Organ 2019;97(8):548–562. DOI: 10.2471/BLT.18.228486
  3. Inhorn MC, Patrizio P. Infertility around the globe: new thinking on gender, reproductive technologies and global movements in the 21st century. Human reproduction update 2015;21(4):411–426. DOI: 10.1093/humupd/dmv016
  4. Novy MJ, Eschenbach DA, Witkin SS. Infections as a cause of infertility. Glob Libr Women's Med 2008. DOI: 10.3843/GLOWM.10328
  5. James C, Harfouche M, Welton NJ, et al. Herpes simplex virus: global infection prevalence and incidence estimates, 2016. Bull World Health Organ 2020;98(5):315–329. DOI: 10.2471/BLT.19.237149
  6. Jaton K, Bille J, Greub G. A novel real-time PCR to detect Chlamydia trachomatis in first-void urine or genital swabs. J Med Microbiol 2006;55(12):1667–1674. DOI: 10.1099/jmm.0.46675-0
  7. Chaudhary N, Kalyan R, Singh M, et al. Prevalence of reproductive tract infections in women attending a tertiary care center in northern India with special focus on associated risk factors. Indian J Sex Transm Dis AIDS 2019;40(2):113. DOI: 10.4103/ijstd.IJSTD_17_16
  8. Diadhiou M, Ba Diallo A, Barry MS, et al. Prevalence and risk factors of lower reproductive tract infections in symptomatic women in Dakar, Senegal. Infect Dis (Auckl) 2019;12:1178633719851825. DOI: 10.1177/1178633719851825
  9. Nandan D, Misra SK, Sharma A, et al. Estimation of prevalence of RTIs/STDs among women of reproductive age group in district Agra. Indian J Community Med 2002;27(3):110.
  10. Kosambiya JK, Desai VK, Bhardwaj P, et al. RTI/STI prevalence among urban and rural women of Surat: A community-based study. Indian J Sex Transm Dis AIDS 2009;30(2):89. DOI: 10.4103/0253-7184.62764
  11. Patel V, Pednekar S, Weiss H, et al. Why do women complain of vaginal discharge? A population survey of infectious and pyschosocial risk factors in a South Asian community. Int J Epidemiol 2005;34(4):853–862. DOI: 10.1093/ije/dyi072
  12. Sharma S, Saxena V, Mundhra R, et al. Pattern and clinico-epidemiological profile of female patients of RTI/STIs attending an STI clinic in Uttarakhand, India. J Family Med Prim Care 2022;11(11):7357–7361. DOI: 10.4103/jfmpc.jfmpc_1397_22
  13. Sawant V, Jaiswal S, Desai M. Impact of socioeconomic and demographic factors on reproductive tract infections during reproductive age group (18–45 years). J South Asian Feder Obst Gynae 2018;11(4):246–248. DOI: 10.5005/jp-journals-10006-1699
  14. Gupta U, Sinha P, Inam L, et al. Socio-demographic profile of reproductive tract infections and sexually transmitted diseases in reproductive aged women. Int J Reprod Contracept Obstet Gynecol 2015;4(3):596–600. DOI: 10.18203/2320-1770.ijrcog20150058
  15. Kafle P, Bhattarai SS. Prevalence and factors associated with reproductive tract infections in gongolia village, Rupandehi district, Nepal. Adv Public Health 2016;2016. DOI: 10.1155/2016/8063843
  16. Hassan HE. Infertility profile, psychological ramifications and reproductive tract infection among infertile women, in northern Upper Egypt. J Nurs Educ Pract 2016;6(4):92. DOI: 10.5430/jnep.v6n4p92
  17. Usharani N, Swetha D. Clinical and microscopic correlation of abnormal vaginal discharge. Int J Contemp Med Res 2021;10(3):909–915. DOI: 10.18203/2320-1770,ijrcog20210706
  18. Balakrishnan S, Carolin A, Sudharsan B, et al. The prevalence of reproductive tract infections based on the syndromic management approach among ever-married rural women in Kancheepuram District, Tamil Nadu: a community-based cross-sectional study. Cureus 2022;14(3):e23314. DOI: 10.7759/cureus.23314
  19. Bhilwar M, Lal P, Sharma N, et al. Prevalence of reproductive tract infections and their determinants in married women residing in an urban slum of North-East Delhi, India. J Nat Sci Biol Med 2015;6(Suppl 1):S29. DOI: 10.4103/0976-9668.166059
  20. Rani V, Dixit AM, Singh NP, et al. KAP study on reproductive tract infections (RTIs) among married women (15-44 years) in rural area of Etawah, Uttar Pradesh. Indian J Community Health [Internet] 2016;28(1):78–83.
  21. Thekdi Komal P, Mehta Prakash I, Thekdi Pukur I, et al. Fertility profile, anxiety, depression of married women and its association with reproductive tract infections in the rural area of Surendranagar District. Sch J App Med Sci 2014;2(1A):104–108. DOI: 10.36347/sjams.2014.v02i01.0020
  22. Wang H, Huang Z, Wu Z, et al. An epidemiological study on vaginitis in 6,150 women of reproductive age in Shanghai. New Microbiol 2017;40(2):113–118. PMID: 28255605.
  23. Liu J, Zeng M, Yang L, et al. Prevalence of reproductive tract infections among women preparing to conceive in Chongqing, China: trends and risk factors. Reprod Health 2022;19(1):1–9. DOI: 10.1186/s12978-022-01502-x
  24. Le MT, Nguyen TLN, Le DD, et al. Is genital tract infection related to tubal diseases in infertile Vietnamese women? J Infect Dev Ctries 2019;13(10):906–913. DOI: 10.3855/jidc.11632
  25. Lan PT, Lundborg CS, Phuc HD, et al. Reproductive tract infections including sexually transmitted infections: a population-based study of women of reproductive age in a rural district of Vietnam. Sex Transm Infect 2008;84(2):126–132. DOI: 10.1136/sti.2007.027821
  26. Dhont N, Luchters S, Muvunyi C, et al. The risk factor profile of women with secondary infertility: an unmatched case-control study in Kigali, Rwanda. BMC Womens Health 2011;11(1):1–7. DOI: 10.1186/1472-6874-11-32
  27. Wójkowska-Mach J, Pomorska-Wesołowska M, Romanik M, et al. Prevalence and antimicrobial susceptibility profiles of microorganisms associated with lower reproductive tract infections in women from Southern Poland-retrospective laboratory-based study. Int J Environ Res Public Health 2021;18(1):335. DOI: 10.3390/ijerph18010335
  28. Peters BM, Yano J, Noverr MC, et al. Candida vaginitis: when opportunism knocks, the host responds. PLoS Pathog 2014;10(4):e1003965. DOI: 10.1371/journal.ppat.1003965
  29. Ranjit E, Raghubanshi BR, Maskey S, et al. Prevalence of bacterial vaginosis and its association with risk factors among nonpregnant women: a hospital based study. Int J Microbiol 2018;2018:8349601. DOI: 10.1155/2018/8349601
  30. Parpillewar MB, Singh S. A comparative study of prevalence of Chlamydia trachomatis infection among infertile and fertile women at a tertiary care center. Arch Med Health Sci 2021;9(1):39–43. DOI: 10.4103/amhs.amhs_123_20
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