International Journal of Infertility & Fetal Medicine

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VOLUME 6 , ISSUE 2 ( May-August, 2015 ) > List of Articles

RESEARCH ARTICLE

Effect of Tuberculosis on Ovarian Reserve of Patients undergoing in vitro Fertilization

Prabhjot Singh Hans, Mohan Lal Swarankar, Swati Garg, Manisha Chowdhary, Karnika Tiwari

Citation Information : Hans PS, Swarankar ML, Garg S, Chowdhary M, Tiwari K. Effect of Tuberculosis on Ovarian Reserve of Patients undergoing in vitro Fertilization. Int J Infertil Fetal Med 2015; 6 (2):73-83.

DOI: 10.5005/jp-journals-10016-1105

License: CC BY-NC 4.0

Published Online: 01-04-2012

Copyright Statement:  Copyright © 2015; The Author(s).


Abstract

Aim

To assess ovarian reserve, in infertile women with genital tuberculosis, planning to undergo in vitro fertilization (IVF) and to compare it with infertile women without genital tuberculosis, planning to undergo IVF.

Materials and methods

The study group consisted of 100 women with genital tuberculosis and the control group of 100 women who had no present or past history of tuberculosis. A diagnosis of genital tuberculosis was made based either on the results of tests performed from an endometrial aspiration sample or on histopathologic, hysterosalpingography, hysteroscopy, or laparoscopy findings. Basal ovarian reserve studies included measuring serum levels of follicle-stimulating hormone (FSH), luteinizing hormone (LH), and E2 on day 3 of a natural cycle. On the same day, the participants underwent a transvaginal ultrasound examination by means of a two-dimensional 5.0 MHz probe fitted to a Toshiba Famio 5. Ovarian volume and number of antral follicles were estimated for each ovary on the same day of hormonal assessment. Control participants underwent the same tests on day 2 or 3 of their menstrual cycle. Unpaired or independent t-test and Chi-square test were used for statistical analysis.

Results

The present study highlights that women with genital tuberculosis have poor ovarian reserve in comparison to women of similar age without tuberculosis.

Conclusion

It can be concluded that there is no single absolute method of assessing ovarian reserve, but a combination of methods can closely predict the outcome of IVF cycles in women with genital tuberculosis.

How to cite this article

Hans PS, Swarankar ML, Garg S, Chowdhary M, Tiwari K. Effect of Tuberculosis on Ovarian Reserve of Patients undergoing IVF. Int J Infertil Fetal Med 2015;6(2):73-83.


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