International Journal of Infertility & Fetal Medicine

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VOLUME 6 , ISSUE 3 ( September-December, 2015 ) > List of Articles

RESEARCH ARTICLE

Association of Ultrasound Estimated Fetal Weight between 10th and 50th Centile in Third Trimester with the Risk of Spontaneous Preterm Delivery

Muralidhar V Pai, Caroline R Mathias

Citation Information : Pai MV, Mathias CR. Association of Ultrasound Estimated Fetal Weight between 10th and 50th Centile in Third Trimester with the Risk of Spontaneous Preterm Delivery. Int J Infertil Fetal Med 2015; 6 (3):108-111.

DOI: 10.5005/jp-journals-10016-1111

License: CC BY-NC 4.0

Published Online: 01-08-2012

Copyright Statement:  Copyright © 2015; The Author(s).


Abstract

Objective

To find out the association of ultrasound estimated fetal weight (UEFW) between 10th and 50th centile, in early third trimester and the risk of spontaneous preterm delivery.

Materials and methods

Fetal weight of 965 women with singleton pregnancy was estimated between 28 and 34 weeks. Women with multiple gestation, medical disorders, fetal anomalies and induced labor were excluded. Values of UEFW were converted into centile values and multiples of median (MoM) for each gestational age. The risk of spontaneous preterm delivery was correlated with the UEFW.

Results

Out of 965 subjects 62 were either excluded as per exclusion criteria or lost for follow-up. Out of 91 subjects with fetal weights ≤10th centile 17 (18.7%, OR 1.82, p-value 0.003) and out of 180 with that ≤20th centile 29 (16.1% OR 1.51, p-value 0.040) had preterm delivery. When the deviation was below 0.85 MoM, 15 out of 73 (20.5% OR 2.08, p-value 0.024) subjects had preterm delivery.

Conclusion

When UEFW in early third trimester is below 20th centile or below 0.80 MoM the risk for spontaneous preterm delivery increases, hence, it may be prudent to be vigilant when the fetal weight is between 10th and 20th centile to avoid preterm delivery.

How to cite this article

Pai MV, Mathias CR. Association of Ultrasound Estimated Fetal Weight between 10th and 50th Centile in Third Trimester with the Risk of Spontaneous Preterm Delivery. Int J Infertil Fetal Med 2015;6(3):108-111.


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  1. Ultrasound estimated fetal weight slightly below the median is associated with increased risk of spontaneous preterm birth. Prenat Diagn 2012 Jun;32(6):588-591.
  2. Impairment of growth in fetuses destined to deliver preterm. Am J Obstet Gynecol 2001 Aug;185(2):463-467.
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  4. Screening to prevent spontaneous preterm birth: systematic reviews of accuracy and effectiveness literature with economic modelling. Health Technol Assess 2009 Sep;13(43):1-627.
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