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VOLUME 4 , ISSUE 2 ( May-August, 2013 ) > List of Articles


Diminished Ovarian Reserve, Causes, Assessment and Management

Mala Arora, Mandeep Kaur

Citation Information : Arora M, Kaur M. Diminished Ovarian Reserve, Causes, Assessment and Management. Int J Infertil Fetal Med 2013; 4 (2):45-55.

DOI: 10.5005/jp-journals-10016-1060

License: CC BY-NC 4.0

Published Online: 01-12-2015

Copyright Statement:  Copyright © 2013; The Author(s).


How to cite this article

Kaur M, Arora M. Diminished Ovarian Reserve, Causes, Assessment and Management. Int J Infertility Fetal Med 2013;4(2):45-55.

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  1. Declining estimates of infertility in the United States: 1982-2002. Fertil Steril 2006;86:516-523.
  2. Delaying childbearing: effect of age on fecundity and outcome of pregnancy. BMJ 1991;302:1361-1365.
  3. The time is now for a new approach to primary ovarian insufficiency. Fertil Steril 2012;95:1890-1897.
  4. Systemic adversities of ovarian failure. J Soc Gynecol Investig 2001;8:S7-S9.
  5. Is early natural menopause a biologic marker of health and aging? Am J Public Health 1989;79:709-714.
  6. Present and future options for the preservation of fertility in female adolescents with cancer. Endocr Dev 2005;8:166-175.
  7. A syndrome of infantilism, congenital webbed neck, and cubitus valgus. Endocrinology 1938;23:566.
  8. The effect of smoking on oogenesis, fertilization and implantation. Semin Reprod Endocrinol 1989;7:291-304.
  9. Effect of smoking on ovarian reserve and ovarian stimulation in in vitro fertilization and embryo transfer. Hum Reprod 1998;13:2192-2198.
  10. Constituents of cigarette smoke inhibit human granulosa cell aromatase. Fertil Steril 1986;46:232-236.
  11. Vanderburgh. Pregnancy after uterine artery embolization for leiomyomata: The Ontario Multicenter Trial. Obstet Gynecol 2005;105:67-76.
  12. Premature ovarian failure. In: Adashi EY, Rock JA, Rosenwaks Z, editors. Reproductive endocrinology, surgery and technology. Philadelphia: Lippincott-Raven 1996;1393-1410.
  13. Clinical features of young women with hyper-gonadotropic amenorrhea. Fertil Steril 1990;53:804-810.
  14. Premature ovarian failure in galactosaemia: pathophysiology and clinical management. Pathol Biol (Paris) 2003;51:47-56.
  15. Ovulation induction with clomiphene citrate in a woman with premature ovarian failure. A case report. J Reprod Med 1988;33:559-562.
  16. Mumps oophoritis: a cause of premature menopause. Fertil Steril 1975;26:655-659.
  17. Ovarian function before and after salpingectomy in artificial reproductive technology patients. Hum Reprod 2000;15:142-144 (level II-3).
  18. Prophylactic salpingectomy does not impair the ovarian response in IVF treatment. Hum Reprod 2001161135-113. (level I).
  19. Environmental toxicants and female reproduction. Fertil Steril 1998;70:613-622.
  20. The follicle-stimulating hormone receptor gene is polymorphic in premature ovarian failure and normal controls. Fertil Steril 1995;64:518-524.
  21. Oocyte apoptosis: like sand through an hourglass. Dev Biol 1999;213:1-17.
  22. Evaluation and treatment of low responders in assisted reproductive technique: a challenge to meet. J Assist Reprod Genet 2000;17:357-373.
  23. Optimum number of oocytes for a successful first IVF treatment cycle. Reprod Biomed Online 2006;13:476-480.
  24. Factors that affect outcome of in vitro fertilization. Lancet 1996;348:1402-1406.
  25. Poor responders to ovulation induction: is proceeding to in vitro fertilization worthwhile? Hum Reprod 1999;14:964-969.
  26. Strategies for ascertaining ovarian reserve among women suspected of subfertility. Int J Fertil Womens Med 2000;45:215-224.
  27. Intercycle variability of ovarian reserve tests: results of a prospective randomized study. Hum Reprod 2004;19:590-595.
  28. A moderately elevated day 3 FSH concentration has limited predictive value, especially in younger women. Hum Reprod 2002;17:118-123.
  29. The predictive value for in vitro fertility delivery rates is greatly impacted by the method used to select the threshold between normal and elevated basal follicle-stimulating hormone. Fertil Steril 2008;89:868-878.
  30. Executive summary: stages of Reproductive Aging Workshop (STRAW). Fertil Steril 2001;76:874-878.
  31. Taking a basal follicle-stimulating hormone history is essential before initiating in vitro fertilization. Fertil Steril 2005;83:37-41.
  32. Prognostic value of day 3 estradiol on in vitro fertilization outcome. Fertil Steril 1995;64:1136-1140.
  33. High reproducibility of serum anti-mullerian hormone measurements suggests a multi-staged follicular secretion and strengthens its role in the assessment of ovarian follicular status. Hum Reprod 2005;20:923.
  34. Serum antimullerian hormone levels: a novel measure of ovarian reserve. Hum Reprod 2002;17:3065-3071.
  35. Anti-mullerian hormone (AMH) as a predictive marker in assisted reproductive technology (ART). Hum Reprod Update 2010;16:113-130.
  36. ESHRE consensus on the definition of ‘poor response ‘to ovarian stimulation for in vitro fertilization: the bologna criteria. Hum Reprod 2011;26: 1616-1624.
  37. Evaluation of the utility of multiple endocrine and ultrasound measures of ovarian reserve in the prediction of cycle cancellation in a high-risk IVF population. Hum Reprod 2007;22:778-785.
  38. Ultrasound tests of ovarian reserve: a systematic review of accuracy in predicting fertility outcomes. Human Fertility 2009;12(2):95-106.
  39. The clomiphene citrate challenge test for the prediction of poor ovarian response and non-pregnancy in patients undergoing in vitro fertilization: a systematic review. Fertil Steril 2006;86: 807-818.
  40. Ovarian reserve assessment for infertility investigation. ISRN Obstet Gynecol 2012;2012:576385. doi: 10.5402/2012/576385. Epub 2012 Jan 26.
  41. Dynamic tests of ovarian reserve: a systematic review of diagnostic accuracy. Reproductive BioMedicine Online 2009;18(5):717-734.
  42. A systematic review of tests predicting ovarian reserve and IVF outcome. Hum Reprod Update 2006;12:685-718.
  43. ESHRE consensus on the definition of poor response to ovarian stimulation for in vitro fertilization: the bologna criterion. Hum Reprod 2011;26: 1616-1624.
  44. Dose of human menopausal gonadotropin influences the outcome of an in vitro fertilization. Fertil Steril 1987;48:964-968.
  45. Doubling the dose of human menopausal gonadotropin in course of in vitro fertilization treatment cycle in poor responder: a randomized study. Human Reprod 1993;8: 369-373.
  46. Microdose follicular phase gonadotropin releasing hormone agonist compared with luteal phase agonist for ovarian stimulation in in vitro fertilization. Fertil Steril 1999;72: 1018-1023.
  47. A controlled trial of natural cycle versus microdose GnRH flare cycles in poor responders undergoing invitro fertilization. Fertil Steril 2004;81: 1542-1547.
  48. Gonadotropin and gonadotropin receptors during the perimenopause. Eur J Endocrinol Metab 2003;88:3327-3332.
  49. Recombinant luteinizing hormone (rLH) for controlled ovarian hyperstimulation in assisted reproductive cycles. Cochrane Database Syst Rev 2007:CD005070.
  50. Effect of androgen levels on in vitro fertilization cycles. Fertil Steril 2004;81:1713-1714.
  51. The effect of transdermal testosterone gel pre-treatment on controlled ovarian stimulation and IVF outcome in poor responders. Fertil Steril 2011;95: 679-683.
  52. DHEA supplementation in diminished ovarian reserve. Reprod Biol Endocrinol 2001 1;9:67.
  53. Effect of androgen supplementation or modulation on ovarian stimulation outcome in poor responders: a meta-analysis. Reproductive Biomed Online 2011; 22:545-555.
  54. Growth hormone for in vitro fertilization. Cochrane Database Syst Review 2000:CD000099.
  55. The value of growth hormone suppliments in ART for poor ovarian responders. Fertil Steril 2011;96:1069-1076.
  56. Adjuvant low-dose aspirin therapy in poor-responders undergoing IVF: a prospective double blind placebo controlled trial. Fertil Steril 2004;81:556-561.
  57. Interventions for poor responders to controlled ovarian hyperstimulation (COH) in in vitro fertilization. Coch Database Syst Review 2007;(1):CD004379. Review.
  58. Assisted hatching of human embryos: a systematic review and metaanalysis of randomised controlled trials. Hum Reprod Update 2011:17;248-253.
  59. Multicentre observational study on slow cooling oocyte cryopreservation: clinical outcome. Fertil Steril 2010;94:1662-1668.
  60. Follicles are found in the ovaries of adolescent girls with Turner's syndrome. J Clin Endocrinol Metab 2002;87:3618-3623.
  61. Bone marrow transplantation generates immature oocytes and rescues long-term fertility in a preclinical mouse model of chemotherapy-induced premature ovarian failure. J Clin Oncol 2007;22:3198-3204.
  62. Production of offspring from a germline stem cell line derived from neonatal ovaries. Nat Cell Biol 2009;5:631-636.
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