Aim: The aim of the study is to identify the impact of paternal age on semen parameters and reproductive outcomes of intracytoplasmic sperm injection (ICSI). Materials and methods: This retrospective study involves 229 patients and 266 cycles who came for ICSI between March 2020 and December 2021 at A4 Fertility Center, Chennai. Semen parameters were determined according to the World Health Organization (WHO) manual 2010, fifth edition, using a Makler chamber. The study is assessed until the blastocyst rate. The paternal age is classified into five subgroups: MI: ≤29 years; MII: 30–34 years; MIII: 35–39 years; MIV: 40–44 years; MV: ≥45 years. The semen parameters (concentration, progressive motility, and normal forms), fertilization rate, and blastocyst rate were compared between the five age-groups. Results: We found that final outcomes, including clinical pregnancy rate (p = 0.041) and miscarriage rates (p = 0.023), were statistically significant when the groups were compared. Ongoing pregnancy rate (p = 0.0003) was highly statistically significant between different male age-groups. Sperm normal forms (p = 0.945), concentration (p = 0.557), progressive motility (p = 0.619), fertilization rate (p = 0.431), blastocyst rate (p = 0.443), and implantation rate (p = 0.182) were not significantly different between the age-groups. Conclusion: Advanced paternal age affects clinical pregnancy and ongoing pregnancy but does not appear to affect semen parameters, fertilization, blastocyst rate, and implantation rates.