Aim and background: The global incidence of cancer is on the rise and with the advancement of cancer care, the survival of cancer patients has also improved. Addressing the fertility needs of survivors is also of paramount importance to improving their quality of life. Case description: We present a case of a young lady with osteosarcoma who was referred to our center for fertility preservation and controlled ovarian stimulation (COS) was done using the antagonist protocol, followed by in vitro fertilization and embryo cryopreservation for future use. Conclusion: Embryo cryopreservation in cancer patients is a well-established method of fertility preservation. In regards to oncofertility, evidence supports a multidisciplinary approach, early referral to a fertility specialist, and individualized discussion on options for fertility preservation without compromising the cancer treatment. Clinical significance: This case highlights the need to include discussions on fertility preservation in oncology patients by the primary care providers and the options available for the patients.