International Journal of Infertility & Fetal Medicine

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VOLUME 13 , ISSUE 2 ( May-August, 2022 ) > List of Articles


Unraveling Chronic Endometritis: A Review

Sharmistha Sarkar, TK Aleyamma, Mohan S Kamath

Keywords : Recurrent implantation failure, Recurrent pregnancy loss, Unexplained infertility, Transvaginal sonography

Citation Information : Sarkar S, Aleyamma T, Kamath MS. Unraveling Chronic Endometritis: A Review. Int J Infertil Fetal Med 2022; 13 (2):82-86.

DOI: 10.5005/jp-journals-10016-1279

License: CC BY-NC 4.0

Published Online: 16-06-2022

Copyright Statement:  Copyright © 2022; The Author(s).


Chronic endometritis (CE) is a pathology associated with persistent inflammation of the endometrial lining. The symptomatology of CE is usually mild or absent. CE is emerging as one of the main causative factors for altering the endometrial receptivity, which negatively impacts the process of implantation. It is mainly associated with unexplained infertility, recurrent miscarriages, and recurrent implantation failures. While immunohistochemical CD 138 staining is the gold standard for the diagnosis of CE, conventional tissue staining, hysteroscopy, transvaginal color Doppler, and culture sensitivity are other useful diagnostic modalities. Targeted or empirical antimicrobial therapy is effective for treatment in women with CE. Reproductive outcomes may improve following treatment with antimicrobial agents.

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