Purpose: Poor responder is a quasi-cluster of patients whose management has confounded clinicians. Luteal phase stimulation as a solution is proposed on a new principle of follicular development. Case description: Mrs. X, a 34-year-old woman with an anti-Mullerian hormone (AMH) of 0.86 ng/mL and a history of failed in vitro fertilization (IVF) with the recovery of one egg was stimulated in the luteal phase. The patient's ovarian stimulation was done with menopur 375 IU, cetrotide 0.25 mg was added after 8 days. The stimulation lasted for 15 days. Results: There were seven oocytes recovered, two blastocysts were formed and transferred in a freeze–thaw cycle. This resulted in a live-born preterm fetus at 27 weeks in view of bleeding placenta previa. Conclusion: Luteal phase stimulation can be another reasonable solution in the long list of stimulation regimens for patients who are poor responders.
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