Role of 3D and 3D Power Doppler to Assess Endometrial Receptivity in IUI Cycles
Chaitanya B Nagori
Citation Information :
Nagori CB. Role of 3D and 3D Power Doppler to Assess Endometrial Receptivity in IUI Cycles. Int J Infertil Fetal Med 2010; 1 (1):19-24.
The assessment of the endometrial receptivity at the time of human chorionic gonadotrophin (hCG) is one of the key factors for success of all ART procedures.
Aim
To assess, if 3D and 3D power Doppler assessment of endometrial receptivity before giving hCG, helps improving pregnancy rates in superovulation with IUI cycles.
Settings and Design
A prospective randomized study of 2500 cycles of IUI was done over a period of twelve months for pre-hCG endometrial assessment.
Method
Endometrial assessment was done on Voluson 730 Expert, (Wipro GE) using transvaginal multifrequency volume probe 5 to 9 MHz. When follicles and endometrium were considered mature by 2D US and color Doppler, 3D and 3D power Doppler assessment of the endometrium was done before giving hCG. These values were evaluated for conception and nonconception groups.
Results
Conception rates were higher, when endometrial volume was between 3 and 7 cc. In our study, we have found endometrial FI > 20 and endometrial VFI > 40 as most optimum.
Conclusions
3D ultrasound is accurate for volume assessment of endometrium. 3D and 3D PD, when used with 2D US and color Doppler for pre-hCG endometrial assessment, it would definitely improve implantation rates in IUI cycles.
The ‘steel’ or ‘teflon’ endometrium–ultrasound visualization of endometrial vascularity in IVF patients and outcome. Presented at the third World Congress of Ultrasound in Obstetrics and Gynecolgy. Ultrasound Obstet Gynecol 1993;3(Suppl 2):10.
Transvaginal three-dimensional ultrasound reproducibility of ovarian and endometrial volume measurements. Fertil Steril 1996;66:718-22.
Assessment of endometrial volume by three-dimensional ultrasound prior to embryo transfer: Clues to endometrial receptivity. Hum Reprod 1999;14:2851-54.
Assessment of endometrial receptivity by transvaginal color Doppler and three dimensional power Doppler ultrasonography in patients undergoing in vitro fertilization procedures. J Ultrasound Med 2001;20:125-34.
Luteal phase defect: Comparison between Doppler velocimetry, histological and hormonal markers. Ultrasound Obstet Gynecology 1997;9:105-12.
Endometrial thickness, morphology, vascular penetration and velocimetry in predicting implantation in an in vitro fertilization program. Ultrasound Obstet Gynecol 1995;6:191-98.
Assessment of uterine receptivity by endometrial-subendometrial blood flow distribution pattern in women undergoing IVF-ET. Fertil Steril 2002;78:245-51.
The role of endometrial and subendometrial blood flows measured by three dimensional power Doppler ultrasound in prediction of pregnancy during IVF treatment. Hum Reprod. 2006;21(1):164-70.
Relationship between uterine blood flow and endometrial and subendometrial blood flows during stimulated and natural cycles. Fertil Steril 2006;85(3):721-27.
Detection of subendometrial vascularization flow index by three-dimensional ultrasound may be useful for predicting pregnancy rate for patients undergoing in vitro fertilizationembryo transfer. Fertil Steril 2003;79(3):507-11.